Updating the icrp human respiratory tract model Gambar adult 18 xxx

A single generic model structure that depicts all potentially important systemic repositories and paths of transfer of all elements of interest in radiation protection would be too complex to be of practical use.

However, generic model structures have been used in previous ICRP documents to represent the systemic biokinetics of groups of elements, typically chemical families, known (or expected to have) qualitatively similar behaviour in the body.

Since these publications, ICRP has continuously improved the accuracy of the models published.For absorption to blood, the main changes introduced in ICRP Publication 130 are: A systemic model describes the time-dependent distribution and retention of a radionuclide in the body after absorption to blood and systemic circulation, and its excretion from the body.In contrast to ICRP’s current and past biokinetic models describing the behaviour of radionuclides in the respiratory and alimentary tracts, ICRP’s systemic models have generally been element-specific with regard to model structure as well as parameter values.New models are being produced and will be used in the new series of ICRP publications (OIR Series and EIR Series).These new models are briefly described below: The Human Respiratory Tract Model (HRTM) described in Publication 66 [1] has been updated in ICRP Publication 130 [13] to take account of data accumulated since its publication, although the basic features of the model remain unchanged.

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